Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease with an incidence of 1 in 400 to 1000. The disease is genetically heterogeneous. with two genes identified: PKD1 (16p13. 3) and PKD2 (4q21). https://megavitamines.shop/product-category/benfotiamine/